We will open the conference by challenging the Threat Modeling Manifesto with the people who helped shape it. Moderated by Stephen de Vries, Adam Shostack, Irene Michlin, Kim Wuyts, and Izar Tarandach, the panel will assess whether its human-centric principles still hold as AI reshapes software architecture, secure development, and risk analysis. We will test how agentic systems, AI-assisted tooling, automated threat identification, and probabilistic controls affect collaboration, system understanding, design decisions, and accountability. The objective is to determine whether the Manifesto requires amendment, a stronger interpretation, or explicit safeguards for AI-driven engineering environments.